Mitochondrial Dysfunction and Alzheimer’s Disease
نویسندگان
چکیده
منابع مشابه
Orbitofrontal Dysfunction Discriminates Behavioral Variant Frontotemporal Dementia from Alzheimers Disease
Background: Behavioral variant frontotemporal dementia (bvFTD) patients show prefrontal cortex dysfunction and atrophy. Methods: We investigated whether executive function in conjunction with prefrontal cortex atrophy discriminates bvFTD and Alzheimer’s disease (AD) patients efficiently at presentation. Results: AD and bvFTD patients were distinguishable by 89.5% on their performance of 3 execu...
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To date, one of the most discussed hypotheses for Alzheimer's disease (AD) etiology implicates mitochondrial dysfunction and oxidative stress as one of the primary events in the course of AD. In this review we focus on the role of mitochondria and mitochondrial DNA (mtDNA) variation in AD and discuss the rationale for the involvement of mitochondrial abnormalities in AD pathology. We summarize ...
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ژورنال
عنوان ژورنال: Open Journal of Endocrine and Metabolic Diseases
سال: 2013
ISSN: 2165-7424,2165-7432
DOI: 10.4236/ojemd.2013.32a003